Sex determining region y-box 2
WebSex determining region Y-box 2 is a prognostic factor for head and neck squamous cell carcinoma: Evidence from 11 published investigations The findings of this meta-analysis … Web14 Aug 2024 · Sex-determining region Y-box 2 (SOX2), a high mobility group (HMG) DNA-binding domain, is mapped to human chromosome 3q26.3–q27 and belongs to a key transcription factor . SOX2 regulates the self-renewal and pluripotency of undifferentiated stem cells such as human embryonic stem cells and plays an important role in …
Sex determining region y-box 2
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Web21 Mar 2024 · GeneCards Summary for SRY Gene. SRY (Sex Determining Region Y) is a Protein Coding gene. Diseases associated with SRY include 46,Xx Sex Reversal 1 and 46,Xy Sex Reversal 1 . Among its related … Web8 Sep 2015 · The transcription factor sex determining region (Y SRY)-box 2 (SOX2) is known to play a crucial role in the maintenance of self renewal or pluripotency of undifferentiated embryonic and neuronal stem cells. An elevated expression of SOX2 has been correlated with poor prognosis of esophageal squamous cell carcinoma (ESCC).
Web21 Mar 2024 · SOX2 (SRY-Box Transcription Factor 2) is a Protein Coding gene. Diseases associated with SOX2 include Microphthalmia, Syndromic 3 and Septooptic Dysplasia.Among its related pathways are Gene expression (Transcription) and Signaling by WNT.Gene Ontology (GO) annotations related to this gene include DNA-binding … Web16 Jul 2015 · Western blot, real-time polymerase chain reaction, and luciferase-based reporter assay were used to study the effect of PAI-039 in the sex-determining region Y-box 2 (Sox2) expression. PAI-039 suppressed the self-renewal capability of head and neck cancer-TICs derived from head and neck cancer cell lines through the inhibition of Sox2 …
WebSex-determining region Y-box 2 is proposed to be a key transcription factor in embryonic stem cells. The known roles of sex-determining region Y-box 2 in development and cell … WebSOX2 gene SRY-box transcription factor 2 Normal Function The SOX2 gene provides instructions for making a protein that plays a critical role in the formation of many …
Web29 Jul 2024 · The gene of sex-determining region Y-box 2 (SOX2) is located on chromosome 3p26.3-q27, and encodes a protein of 317 amino acids comprising of three main domains: high mobility group (HMG) domain ...
WebThe development of lung cancer is a complex process that involves many genetic and epigenetic changes. Sex-determining region Y (SRY)-box (SOX) genes encode a family of proteins that are involved in the regulation of embryonic development and cell fate determination. SOX1 is hypermethylated in human cancers. However, the role of SOX1 in … my 365 office downloadWeb9 Mar 2024 · transcription factor Sox-2, SRY (sex determining region Y)-box 2, SRY-box containing gene 2, transcription factor SOX2 GeneRIFs: Gene References Into Functions … how to paint an old barnWeb16 Mar 2016 · UniProtKB unreviewed (TrEMBL) Organism. Homo sapiens (Human) Amino acids. 317. Protein existence. Predicted. Annotation score. 2/5. how to paint an old china hutchWeb9 Jun 2024 · Background: Sex-determining region Y-box 2 (SOX2) is a transcriptional factor that drives embryonic stem cells to neuroendocrine cells in lung development and is highly expressed in small-cell... how to paint an old cast iron stoveWeb28 Mar 2024 · Sox2 SRY (sex determining region Y)-box 2 [ (house mouse)] Gene ID: 20674, updated on 28-Feb-2024 Summary This intronless gene encodes a member of the SRY … my 365 subscriptionWeb8 Apr 2024 · Sex-determining region Y (SRY)-box (SOX) genes encode a family of proteins that are involved in the regulation of embryonic development and cell fate determination. SOX1 is hypermethylated in human cancers. However, the role of SOX1 in the development of lung cancer is unclear. We used quantitative methylation-specific polymerase chain … how to paint an old deskWeb9 Jun 2024 · Background: Sex-determining region Y-box 2 (SOX2) is a transcriptional factor that drives embryonic stem cells to neuroendocrine cells in lung development and is … my 365 outlook