WebApr 10, 2024 · Acute kidney injury (AKI) is a heterogeneous clinical syndrome with varying causes, pathophysiology and outcomes. Our objective was to incorporate pla… WebMar 17, 2024 · 77 Acute kidney injury (AKI) is a syndrome defined by rapid decline in kidney function from hours to 78 days leading to disruption in metabolic, electrolyte, and fluid homeostasis (1). Between 20-25% 79 of hospitalised adults have AKI, and it is associated with longer duration of stay and a 4-16 fold
Sub-Phenotypes of Acute Kidney Injury: Do We Have Progress for ...
Web1 day ago · Hypertension: a Cardiovascular and Renal Risk Factor in the General Population. Hypertension is highly prevalent in the adult population (≈30%) and the percentage of subjects presenting with hypertension increases markedly with age. 5,19,20 Numerous epidemiological studies have demonstrated that an elevated BP is not only a risk factor … WebKidney diseases, including acute kidney injury (AKI) and chronic kidney disease (CKD), represent a general, public health urgency, causing a heavy burden to global health care systems. Moreover, AKI is a frequent complication of hospitalization, and it is associated with short-term morbidity and mortality rate greater than 50%, as a result of its … quick access cold war
Subphenotypes of acute kidney injury in children
WebJan 20, 2024 · Unfortunately, AKI evaluation is not this simple. Sepsis, cardiac surgery, liver disease, and trauma can all alter kidney function that affects multiple intrarenal and extrarenal systems. These clinical syndromes are not synonymous with the simple laboratory models of volume depletion or renal artery clamping. WebMar 17, 2024 · Background Acute Kidney Injury (AKI) is a multifactorial condition which presents a substantial burden to healthcare systems. There is limited evidence on whether it is seasonal. We sought to investigate the seasonality of AKI hospitalisations in England and use unsupervised machine learning to explore clustering of underlying comorbidities, to … WebApr 10, 2024 · Among 769 AKI patients both LCA and k-Means identified two distinct AKI sub-phenotypes (Classes 1 and 2). The long-term risk for MAKE was higher with class 2 (adjusted hazard ratio 1.41; 95% CI, 1.08 to 1.84; p=0.01) compared with class 1, adjusting for demographics, hospital level factors and KDIGO Stage of AKI.The higher risk of MAKE … quick access counseling